Group Member: Nikolaus Fortelny

Contact Details

• E-Mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
• Phone: +43-1/40160-70066

Research Interests

• Post-translational regulation (PhD thesis focused on proteases)
• (Epi-)genetic regulation of gene expression
• Systems and network biology
• Multi-omics and personalized medicine
• Bioinformatics
• Machine learning

Academic Employment

• 08/2016-currently: Postdoctoral Fellow in the lab of Christoph Bock at CeMM, Vienna, Austria
• 01/2012-05/2016: Graduate Research Assistant in the labs of Chris Overall and Paul Pavlidis at UBC Vancouver, Canada
• 01/2012-05/2016: Teaching Assistant at UBC Vancouver, Canada
• 09/2010—01/2011: Bioinformatician, NeXtProt database, Geneva Bioinformatics SA (Genebio) in Geneva, Switzerland
• 08/2009-07/2010: Graduate Student (MSc) in the Proteomics Informatics group led by Frederique Lisacek at the Swiss Institute of Bioinformatics
• 02/2009-05/2009: Internship at the World Health Organization (WHO) in Geneva, Switzerland

Academic Degrees

• 2016: PhD, University of British Columbia, Vancouver, Canada
• 2010: MSc, University of Geneva, Switzerland
• 2009: BSc, University of Vienna, Austria

Scholarships and Awards

• 09/2014: 4-year PhD Fellowship, UBC Vancouver
• 09/2012: Graduate Student Award, UBC Faculty of Medicine

Publications

• Anania VG, Yu K, Gnad F, Pferdehirt RR, Li J, Ma T, Jeon D, Fortelny N, Forrest W, Ashkenazi A, Overall CM, Lill JR (2016): Uncovering a dual regulatory role for caspases during endoplasmic reticulum stress-induced cell death. Molecular & Cellular Proteomics, mcp.M115.055376 
• Prudova A, auf dem Keller U, Gocheva V, Eckhard U, Butler G, Fortelny N, Lange PF, McLeod J, Olson O, Joyce J and Overall CM (2016): Proteome and N-terminome profiling of cysteine cathepsin substrates in RIP-TAG pancreatic tumors. Cell Reports 16 (6), 1762-1773
• Fortelny N, Pavlidis P and Overall CM (2015): The path of no return—Truncated protein N-termini and current ignorance of their genesis, PROTEOMICS, 0, 1–6
• Fortelny N, Yang S, Pavlidis P, Lange PF* and Overall CM* (2015): Proteome TopFIND 3.0 with TopFINDer and PathFINDer: database and analysis tools for the association of protein termini to pre- and post-translational events, Nucleic Acids Research, 43 (D1): D290-D297
• Fortelny N, Cox JH, Kappelhoff R, Starr AE, Lange PF, Pavlidis P, Overall CM (2014): Network Analyses Reveal Pervasive Functional Regulation Between Proteases in the Human Protease Web, PLOS Biology, 12(5): e1001869
• Prudova A, Serrano K, Eckhard U, Fortelny N, Devine D, Overall, CM (2014): TAILS N-terminomics of human platelets reveal pervasive proteolytic processing and a prominent role of metalloproteinases during storage, Blood, 124, e49–e60

(Google Scholar: https://scholar.google.ca/citations?user=IHjaqgkAAAAJ)